Elabscience

Recombinant Human CD155/PVR/NECL5 Protein (His Tag)(Active)

Product Code:
 
PKSH033563
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
 
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
 

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CodeSizePrice
PKSH033563-10ug10ug£297.00
Quantity:
PKSH033563-50ug50ug£498.00
Quantity:
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Further Information

Abbreviation:
CD155;PVR;NECL5
Accession:
P15151
Activity:
Immobilized Human TIGIT-Fc(Cat: PKSH033510) at 5ug/ml(100 ul/well) can bind Human PVR-His. The ED50 of Human PVR-His is 11.66 ug/ml.
Background:
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV); an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains; a transmembrane segment; and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α; β; γ; and δ) with identical extracellular domains.
Calculated MW:
36.13 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
58 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Trp21-Asn343(Ile340Met)
Target Synonym:
Poliovirus Receptor;Nectin-Like Protein 5;NECL-5;CD155;PVR;PVS
UNIProt ID:
P15151

Documents