Elabscience

Recombinant Mouse CD6/TP120 Protein (His Tag)

Product Code:
 
PKSM041351
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSM041351-10ug10ug£126.00
Quantity:
PKSM041351-50ug50ug£219.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CD6;TP120
Accession:
Q91WN5
Background:
CD6 is a member of the group B scavenger receptor cysteinerich(SRCR) superfamily. CD6 is a type I membrane glycoprotein and contains three extracellularSRCR domains. CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. The majority of peripheral blood T cells, a subsetof B cells, and a subset of neuronal cells express CD6. Mouse CD6 is a 626 amino acid (aa) protein with a 24 aa sequence, a 372 aa extracellular domain, and a204 aa cytoplasmic region. The role of CD6 has not been fully elucidated. However, it appears to play a role as both a costimulatorymolecule in T cell activation and as an adhesion receptor.CD6/ALCAM interactions have been postulated to play a role in thymocyte development. The CD6 intracellular domain contains regions that can interact with SH2 or SH3 containing proteins. However,the signaling pathways have not been elucidated.
Calculated MW:
41.9 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
60-90 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Leu18-Gly396
Target Synonym:
CD6 antigen;Cd6
UNIProt ID:
Q91WN5

Documents