Elabscience

RNF111 Polyclonal Antibody

Product Code:
 
E-AB-18773
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using RNF111 Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using RNF111 Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using RNF111 Polyclonal Antibody at dilution of 1:50(?200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using RNF111 Polyclonal Antibody at dilution of 1:50(?200)

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E-AB-18773-20uL20uL£125.00
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E-AB-18773-60uL60uL£172.00
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E-AB-18773-120uL120uL£237.00
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E-AB-18773-200uL200uL£344.00
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Further Information

Abbreviation:
RNF111
Background:
The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.84 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human RNF111
Purification method:
Antigen affinity purification
Target Synonym:
ARK;Arkadia;DKFZp313E0731;DKFZp686H1966;DKFZp761D081;E3 ubiquitin protein ligase Arkadia;E3 ubiquitin-protein ligase Arkadia;FLJ38008;RING finger protein 111;RN111;RNF 111;RNF111
UNIProt ID:
Q6ZNA4

Documents