FBXO32 Polyclonal Antibody

FBXO32

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

1.44 mg/mL

Unconjugated

IHC 1:30-1:150, ELISA 1:5000-1:10000

Synthetic peptide of human FBXO32

Antigen affinity purification

4833442G10Rik;AI430017;Atrogin 1 ;Atrogin-1;ATROGIN1;Atrophy gene 1;F box only protein 32;F-box only protein 32;F-box protein 32;FBX32;fbxo25;FBXO32;FLJ32424;MAFbx;MGC108443;MGC137646;MGC33610 ;Muscle atrophy F box;Muscle atrophy F box protein;Muscle atrophy F-box protein

Q969P5