Elabscience

GRM2 Polyclonal Antibody

Product Code:
 
E-AB-53395
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human tonsil tissue using GRM2 Polyclonal Antibody at dilution of 1:35(?200)
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Immunohistochemistry of paraffin-embedded Human tonsil tissue using GRM2 Polyclonal Antibody at dilution of 1:35(?200)

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E-AB-53395-20uL20uL£125.00
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E-AB-53395-120uL120uL£237.00
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E-AB-53395-200uL200uL£344.00
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Further Information

Abbreviation:
GRM2
Background:
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.96 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human GRM2
Purification method:
Antigen affinity purification
Target Synonym:
AMPA selective glutamate receptor 2 ;GLUR2;GLURB;Glutamate metabotropic receptor 2;Glutamate receptor homolog;Glutamate receptor metabotropic 2;GPRC1B;GRM2;GRM2;Metabotropic glutamate receptor 2;mGlu2;mGluR2;OTTHUMP00000210984;OTTHUMP00000210986
UNIProt ID:
Q14416

Documents