Elabscience

FBXW5 Polyclonal Antibody

Product Code:
 
E-AB-68018
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of A-549 cells using FBXW5 Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of A-549 cells using FBXW5 Polyclonal Antibody at dilution of 1:1000.

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E-AB-68018-60uL60uL£210.00
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E-AB-68018-120uL120uL£291.00
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E-AB-68018-200uL200uL£431.00
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Further Information

Abbreviation:
FBXW5
Background:
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
42kDa/63kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000
Immunogen:
Recombinant fusion protein of human FBXW5 (NP_061871.1).
ObservedMW:
72kDa
Purification method:
Affinity purification
Target Synonym:
FBXW5;Fbw5
UNIProt ID:
Q969U6

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