Elabscience

PFKFB3 Polyclonal Antibody

Product Code:
 
E-AB-66342
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Immunofluorescence (IF)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunofluorescence analysis of U2OS cells using PFKFB3 Polyclonal Antibody
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Immunofluorescence analysis of U2OS cells using PFKFB3 Polyclonal Antibody

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CodeSizePrice
E-AB-66342-60uL60uL£210.00
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E-AB-66342-120uL120uL£291.00
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E-AB-66342-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
PFKFB3
Background:
The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human PFKFB3 (NP_004557.1).
Purification method:
Affinity purification
Target Synonym:
PFKFB3;IPFK2;PFK2;iPFK-2
UNIProt ID:
Q16875

Documents