Elabscience

PTPRJ Polyclonal Antibody

Product Code:
 
E-AB-65741
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of Raji cells using PTPRJ Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of Raji cells using PTPRJ Polyclonal Antibody at dilution of 1:1000.

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E-AB-65741-60uL60uL£210.00
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E-AB-65741-120uL120uL£291.00
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E-AB-65741-200uL200uL£431.00
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Further Information

Abbreviation:
PTPRJ
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
57kDa/145kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000
Immunogen:
Recombinant fusion protein of human PTPRJ (NP_002834.3).
ObservedMW:
260kDa
Purification method:
Affinity purification
Target Synonym:
PTPRJ;CD148;DEP1;HPTPeta;R-PTP-ETA;SCC1
UNIProt ID:
Q12913

Documents