Elabscience

IPO4 Polyclonal Antibody

Product Code:
 
E-AB-66496
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Immunofluorescence (IF)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunofluorescence analysis of HeLa cells using IPO4 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Immunofluorescence analysis of HeLa cells using IPO4 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

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E-AB-66496-60uL60uL£210.00
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E-AB-66496-120uL120uL£291.00
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E-AB-66496-200uL200uL£431.00
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Further Information

Abbreviation:
IPO4
Background:
Importin-4is aproteinthat in humans is encoded by theIPO4gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human IPO4 (NP_078934.3).
Purification method:
Affinity purification
Target Synonym:
IPO4;Imp4
UNIProt ID:
Q8TEX9

Documents