Elabscience

ZP3 Polyclonal Antibody

Product Code:
 
E-AB-66017
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Immunofluorescence (IF)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunofluorescence analysis of Rat oophoroma cells using ZP3 Polyclonal Antibody at dilution of  1:100. Blue: DAPI for nuclear staining.
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Immunofluorescence analysis of Rat oophoroma cells using ZP3 Polyclonal Antibody at dilution of  1:100. Blue: DAPI for nuclear staining.

Immunofluorescence analysis of Rat oophoroma cells using ZP3 Polyclonal Antibody at dilution of  1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of Rat oophoroma cells using ZP3 Polyclonal Antibody at dilution of  1:100. Blue: DAPI for nuclear staining.

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E-AB-66017-60uL60uL£210.00
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E-AB-66017-120uL120uL£291.00
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E-AB-66017-200uL200uL£431.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
ZP3
Background:
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus; however, sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome. Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3, including the above described variation, and maps closely to this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:200
Immunogen:
A synthetic peptide of human ZP3 (NP_001103824.1).
Purification method:
Affinity purification
Target Synonym:
ZP3;ZP3A;ZP3B;ZPC;Zp-3
UNIProt ID:
P21754

Documents