Elabscience

ASCC1 Polyclonal Antibody

Product Code:
 
E-AB-66600
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of Rat pancreas using ASCC1 Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of Rat pancreas using ASCC1 Polyclonal Antibody at dilution of 1:1000.

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E-AB-66600-60uL60uL£210.00
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E-AB-66600-120uL120uL£291.00
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E-AB-66600-200uL200uL£431.00
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Further Information

Abbreviation:
ASCC1
Background:
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
41kDa/45kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human ASCC1 (NP_001185727.1).
ObservedMW:
46kDa
Purification method:
Affinity purification
Target Synonym:
ASCC1;ASC1p50;CGI-18;SMABF2;p50
UNIProt ID:
Q8N9N2

Documents