Elabscience

GRM8 Polyclonal Antibody

Product Code:
 
E-AB-67515
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using GRM8 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using GRM8 Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-67515-60uL60uL£210.00
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E-AB-67515-120uL120uL£291.00
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E-AB-67515-200uL200uL£431.00
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Further Information

Abbreviation:
GRM8
Background:
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
55kDa/101kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human GRM8
ObservedMW:
120kDa
Purification method:
Affinity purification
Target Synonym:
GRM8;GLUR8;GPRC1H;MGLUR8;mGlu8
UNIProt ID:
O00222

Documents