Elabscience

BNP Polyclonal Antibody

Product Code:
 
E-AB-67421
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of Rat heart using BNP Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of Rat heart using BNP Polyclonal Antibody at dilution of 1:1000.

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E-AB-67421-60uL60uL£210.00
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E-AB-67421-120uL120uL£291.00
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E-AB-67421-200uL200uL£431.00
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Further Information

Abbreviation:
BNP
Background:
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
14kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human BNP (NP_002512.1).
ObservedMW:
17kDa
Purification method:
Affinity purification
Target Synonym:
NPPB;BNP
UNIProt ID:
P16860

Documents