Elabscience

DNA polymerase eta Polyclonal Antibody

Product Code:
 
E-AB-67345
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunofluorescence analysis of U2OS cells using DNA polymerase eta Polyclonal Antibody
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Immunofluorescence analysis of U2OS cells using DNA polymerase eta Polyclonal Antibody

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E-AB-67345-60uL60uL£210.00
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E-AB-67345-120uL120uL£291.00
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E-AB-67345-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
DNA polymerase eta
Background:
This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
46kDa/78kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human DNA polymerase eta (NP_006493.1).
ObservedMW:
70kDa
Purification method:
Affinity purification
Target Synonym:
POLH;RAD30;RAD30A;XP-V;XPV
UNIProt ID:
Q9Y253

Documents