Elabscience

MAP3K3 Polyclonal Antibody

Product Code:
 
E-AB-66675
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
1 / 1
Immunohistochemistry of paraffin-embedded Human appendix using MAP3K3 Polyclonal Antibody at dilution of 1:100 (40x lens).
❮❯

Immunohistochemistry of paraffin-embedded Human appendix using MAP3K3 Polyclonal Antibody at dilution of 1:100 (40x lens).

No additional charges, what you see is what you pay! *

CodeSizePrice
E-AB-66675-60uL60uL£210.00
Quantity:
E-AB-66675-120uL120uL£291.00
Quantity:
E-AB-66675-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: China.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Abbreviation:
MAP3K3
Background:
This gene product is a 626-amino acid polypeptide that is 96.5% identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:200
Immunogen:
Recombinant fusion protein of human MAP3K3 (NP_976226.1).
Purification method:
Affinity purification
Target Synonym:
MAP3K3;MAPKKK3;MEKK3
UNIProt ID:
Q99759

Documents