Elabscience

Recombinant Beclin 1 Monoclonal Antibody

Product Code:
 
E-AB-81447
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
R02-8D5
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot detection of Beclin 1 in K562,Rat Brain,C6,3T3,Hela cell lysates using Beclin 1 Rabbit mAb(1:1000 diluted).Predicted band size:52kDa.Observed band size:60kDa.
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Western blot detection of Beclin 1 in K562,Rat Brain,C6,3T3,Hela cell lysates using Beclin 1 Rabbit mAb(1:1000 diluted).Predicted band size:52kDa.Observed band size:60kDa.

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E-AB-81447-50uL50uL£184.00
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E-AB-81447-100uL100uL£251.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
Beclin 1
Background:
Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
52kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
Recombinant protein of human Beclin 1
ObservedMW:
52kDa
Purification method:
Affinity Purified
Target Synonym:
APG6;ATG 6;ATG6;ATG6 autophagy related 6 homolog;Bcl-2-interacting protein beclin;Beclin 1 (coiled coil moesin like BCL2 interacting protein);Beclin 1 autophagy related;Beclin-1;Beclin1;BECN 1;Becn1;BECN1;Coiled coil myosin like BCL2 interacting protein;Coiled-coil myosin-like BCL2-interacting protein;GT197;Protein GT197;VPS 30;VPS30
UNIProt ID:
Q14457

Documents