Elabscience

Recombinant Semaphorin 4D Monoclonal Antibody

Product Code:
 
E-AB-81485
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
R05-2E3
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot detection of Semaphorin 4D/CD100 in Jurkat cell lysates using Semaphorin 4D/CD100 Rabbit mAb(1:500 diluted).Predicted band size:96kDa.Observed band size:120kDa.
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Western blot detection of Semaphorin 4D/CD100 in Jurkat cell lysates using Semaphorin 4D/CD100 Rabbit mAb(1:500 diluted).Predicted band size:96kDa.Observed band size:120kDa.

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E-AB-81485-50uL50uL£184.00
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E-AB-81485-100uL100uL£251.00
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Further Information

Abbreviation:
Semaphorin 4D
Background:
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
96kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000
Immunogen:
A synthetic peptide of human Semaphorin 4D
ObservedMW:
120kDa
Purification method:
Affinity Purified
Target Synonym:
A8;BB 18;BB18;CD 100;CD100;CD100 antigen;Coll 4;COLL4;Collapsin 4;Collapsin4;GR3;Leukocyte activation antigen CD100;M sema G;MSEMA;SEM4D;Sema 4d;Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D;Sema H;SEMA J;Sema4d;Semacl 2;Semacl2;SemaH;SEMAJ;Semaphorin 4D;Semaphorin C like 2;Semaphorin H;Semaphorin J;Semaphorin-4D;Semaphorin4D;SemaphorinJ;Semcl 2;Semcl2
UNIProt ID:
Q92854

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