Recombinant Transcription Factor 7 Like 2 Monoclonal Antibody

Product Code:

E-AB-81487

Product Group:

Primary Antibodies

Supplier:

Elabscience

Host Type:

Rabbit

Antibody Isotype:

IgG

Antibody Clonality:

Monoclonal

Antibody Clone:

R09-1D1

Regulatory Status:

RUO

Target Species:

Human

Applications:

Immunohistochemistry- Paraffin Embedded (IHC-P)
Western Blot (WB)

Shipping:

Ice packs

Storage:

Store at -20°C. Avoid freeze / thaw cycles.

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Code	Size	Price

E-AB-81487-50uL

50uL

£184.00

Quantity:

E-AB-81487-100uL

100uL

£251.00

Quantity:

Prices exclude any Taxes / VAT

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Further Information

Abbreviation:

Transcription Factor 7 Like 2

Background:

Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small inTine.

Buffer:

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Calculated MW:

68kDa

Concentration:

300 ug/mL

Conjugation:

Unconjugated

Dilution:

WB 1:500-1:1000 IHC 1:50-1:100

Immunogen:

A synthetic peptide of human TCF-4

ObservedMW:

68kDa

Purification method:

Affinity Purified

Target Synonym:

TCF7L2;HMG box transcription factor 4;HTCF-4;T-cell factor-4 variant X2;T-cell factor 4;Transcription factor 7-like 2;TCF-4

UNIProt ID:

Q9NQB0

Recombinant Transcription Factor 7 Like 2 Monoclonal Antibody

Further Information

Documents