Elabscience

Recombinant Cytochrome P450 2D6 Monoclonal Antibody

Product Code:
 
E-AB-81500
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
R07-3G8
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of CYP2D6 in paraffin-embedded liver cancer tissue using CYP2D6 Rabbit mAb at dilution 1:50
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Immunohistochemistry of CYP2D6 in paraffin-embedded liver cancer tissue using CYP2D6 Rabbit mAb at dilution 1:50

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E-AB-81500-50uL50uL£184.00
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E-AB-81500-100uL100uL£251.00
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Further Information

Abbreviation:
Cytochrome P450 2D6
Background:
CYP2D6(Cytochrome P450 2D6) is also named as CYP2DL1 and belongs to the cytochrome P450 family. It is a monooxygenase that involved in the metabolism of drugs such as antiarrhythmics,adrenoceptor antagonists,and tricyclic antidepressants. CYP2D6 is responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It has 2 isoforms produced by alternative splicing with the molecular weight of 56 kDa and 50 kDa.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
56kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100
Immunogen:
Recombinant protein of human CYP2D6
ObservedMW:
50kDa
Purification method:
Affinity Purified
Target Synonym:
CPD6;CYP2D;CYP2D6;CYP2D7AP;CYP2D7BP;CYP2D7P2;CYP2D8P2;CYP2DL1;CYPIID6;Cytochrome P450 DB1;Cytochrome P450 family 2 subfamily D member 6;Cytochrome P450 family 2 subfamily D polypeptide 6;Debrisoquine 4 hydroxylase;Flavoprotein linked monooxygenase;Microsomal monooxygenase;P450 DB1;P450C2D;P450DB1;Xenobiotic monooxygenase
UNIProt ID:
P10635

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