Elabscience

PerCP/Cyanine5.5 Anti-Mouse CD62L Antibody[Mel14]

Product Code:
 
E-AB-F1011UJ
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a, κ
Antibody Clone:
 
Mel14
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
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C57BL/6 murine splenocytes are stained with PerCP/Cyanine5.5 Anti-Mouse CD62L Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
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C57BL/6 murine splenocytes are stained with PerCP/Cyanine5.5 Anti-Mouse CD62L Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.

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CodeSizePrice
E-AB-F1011UJ-25ug25ug£137.00
Quantity:
E-AB-F1011UJ-100ug100ug£244.00
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Further Information

Abbreviation:
CD62L
Background:
CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
0.2 mg/mL
Conjugation:
PerCP/Cyanine5.5
GeneID:
20343
Target Synonym:
L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
UNIProt ID:
P18337
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 ug/10^6 cells in 100 uL volume].

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