MBL

Anti-CD8b (Rat) mAb Functional Grade

Product Code:
 
MBL-FP30042550
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1 κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
341
Regulatory Status:
 
RUO
Target Species:
 
Rat
Applications:
  • Flow Cytometry
  • Functional Study
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP30042550500 ug£568.00
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Further Information

Background:
The 341 monoclonal antibody specifically reacts with the beta chain of the Rat CD8 molecule. The alpha and beta chains of the CD8 molecule form a heterodimer common on most thymocytes. The CD8 positive T cells of athymic rats and most NK cells express a homodimer composed solely of CD8a. It is reported that macrophages express CD8 alpha and beta chains for signal transduction. CD8 is an antigen co-receptor that interacts with MHC class I molecules on antigen-presenting cells.
Concentration:
1 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
CD8b

Documents

References

Shevach, E. M., Annu Rev Immunol. 18, 423-449 (2000) Wu, L., et al., Nature. 349, 71-74 (1991) Bliss, S. K., et al., J Immunol. 178, 7974-7983 (2007)