MBL

Anti-Foxp3 (Mouse) mAb-APC

Product Code:
 
MBL-FP20818010
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1 κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
3G3
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP20818010100 ug£656.00
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This product comes from: United States.
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Further Information

Background:
The 3G3 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression.Mutations of Foxp3 result in the ?scurfy? mice phenotype.
Concentration:
0.2 mg/mL
Conjugate:
APC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
Foxp3

Documents

References

Ledbetter, J. A., et al., Immunol Rev. 47, 63-90 (1979) Thomas, M. L., Annu Rev Immunol. 7, 339-369 (1989) Simon, D. I., et al., J Clin Invest. 105, 293-300 (2000)