MBL

Anti-CD11a (Mouse) mAb Functional Grade

Product Code:
 
MBL-FP20112550
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rat
Antibody Isotype:
 
IgG2a κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
M17/4
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Flow Cytometry
  • Functional Study
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP20112550500 ug£568.00
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This product comes from: United States.
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Further Information

Background:
The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The M17/4 antibody blocks many of the LFA-1 mediated cell interaction and in vivo it prolongs allograft survival, inhibits the autoimmune response, and reduces graft versus host reactions.
Concentration:
1 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
CD11a

Documents

References

Herling, M., et al. , Blood. 101, 5007-5009 (2003) Peduzzi, E., et al., J Invest Dermatol. 127, 638-645 (2007) Sun, Q., et al. , Blood. 87, 83-92 (1996)