MBL

Anti-TLR4 (CD284) (Human) mAb Functional Grade

Product Code:
 
MBL-FP10882510
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2a κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
HTA125
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Flow Cytometry
  • Functional Study
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP10882510100 ug£458.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Background:
The HTA125 monoclonal antibody specifically reacts with human CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). CD284 is an important molecule in the innate immunity response to bacterial lipoproteins. It is expressed by monocytes, macrophages, and endothelial cells. The HTA125 antibody can block Lipopolysaccharide-induced cytokine production and immunoprecipitate human TLR4.
Concentration:
1 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
TLR4

Documents

References

Hendriks, J., et al., J Exp Med. 198, 1369-1380 (2003) Sakanishi, T., & Yagita, H., Biochem Biophys Res Commun. 393, 829-835 (2010) Gravestein, L. A., et al., Int Immunol. 7, 551-557 (1995)