MBL

Anti-IL-7Ra (CD127) (Human) mAb-PE-Cy5

Product Code:
 
MBL-FP10806510
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1 κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
RDR5
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP10806510100 tests£586.00
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Further Information

Background:
The RDR5 monoclonal antibody specifically reacts with human CD127, a 60-90 kDA type I transmembrane glycoprotein also known as the IL-7 receptor alpha chain. CD127 binds with CD132 (gamma c) to forms the IL-7 receptor that is expressed on mature T cells and immature B cells. Since CD127 expression is downregulated in Treg cells, it can be used as a marker for differentiating them from common T cells. The binding of the RDR5 antibody can be blocked by pre-incubating the cells with human IL-7.
Concentration:
5 uL (0.125 ug)/test
Conjugate:
PE
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
IL-7Ra

Documents

References

Coffman, R. L., Immunol Rev. 69, 5-23 (1983) Allman, D. M., et al., J Immunol. 149, 2533-2540 (1992) Monteith, C. E., et al., Can J Vet Res. 60, 193-198 (1996)