MBL

Anti-CD49d (Human) mAb

Product Code:
 
MBL-FP10662002
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1 κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
9F10
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Flow Cytometry
  • Immunohistochemistry (IHC)
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP1066200225 ug£194.00
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  • Further Information
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Further Information

Background:
The 9F10 monoclonal antibody specifically reacts with human CD49d, the 150 kDA alpha 4 integrin chain. The molecule forms the heterodimer called VLA-4 with integrin beta 1 and another heterodimer with integrin beta 7 that binds fibronectin, VCAM-1, and MadCAM-1. CD49d is expressed on monocytes, lymphocytes, thymocytes, NK cells, B cells, and T cells. It is involved in hematopoietic stem cell differentiation, cell migration, and cell activation. Its absence on Foxp3+ cells make it a useful marker to isolate Treg cell populations.
Concentration:
0.5 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD49d

Documents

References

Bhattacharya, A., et al., J. Immunol. 127, 2488-2495 (1981) Mendiratta, S. K., et al., Immunology. 89, 238-244 (1996) Unternaehrer, J. J., et al., Proc Natl Acad Sci U S A. 104, 234-239 (2007)