MBL

Anti-HEXA (Human) mAb

Product Code:
 
MBL-W158-3
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2a κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
2D7C1C
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
-20°C
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MBL-W158-3100 ul£345.00
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  • Further Information
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Further Information

Applications:
FCM - 1-10 ug/mL
Background:
Beta-hexosaminidase subunit alpha (HEXA) is the alpha subunit of the lysosomal enzyme beta-hexosaminidase. It catalyzes the degradation of the ganglioside GM2 and other molecules containing terminal N-acetyl hexosamines. Mutation of HEXA leads to GM2-gangliosidosis Type I.
Formulation:
1 mg/mL in PBS/50% glycerol, pH 7.2
Gene IDs:
Human: 3073
Immunogen Translated:
Human HEXA expressed Ba/F3 transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening).
Reactivity:
This antibody reacts with human HEXA on Flow cytometry.
Source:
This antibody was purified from hybridoma culture supernatant by Protein A affinity column chromatography.
Target:
HEXA (Human)

Documents

References

1) Kojima, T. and Kitamura,T., Nat. Biotechnol. 17, 487-490 (1999) 2) Mahuran, D. J., Biochim. Biophys. Acta 1096, 87-94 (1991) 3) Myerowitz, R., et. al., PNAS. 82, 7830-7834 (1985)