MBL

Anti-Osteopontin (SPP1) (Human) mAb

Product Code:
 
MBL-W052-3
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2a κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
4A7D
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
-20°C
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MBL-W052-3100 ul£345.00
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  • Further Information
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Further Information

Applications:
FCM - 1-10 ug/mL
Background:
Osteopontin, also known as SPP1, is a secreted phosphoglycoprotein that belongs to the SIBLING family. Osteopontin binds to hydroxyapatite and is involved in anchoring of osteoclasts to the mineral matrix of bones. It also acts as a cytokine that mediates type I immune responses through enhancing the production of interferon-gamma and interleukin-12 while reducing production of interleukin-10. Osteopontin has been identified as a biomarker for ovarian cancer, prostate cancer, and non-small cell lung cancer.
Formulation:
1 mg/mL in PBS/50% glycerol, pH 7.2
Gene IDs:
Human: 6696
Immunogen Translated:
Human Osteopontin (SPP1) expressed Ba/F3 transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening).
Reactivity:
This antibody reacts with human Osteopontin (SPP1) on Flow cytometry.
Source:
This antibody was purified from hybridoma culture supernatant by Protein A affinity column chromatography.
Target:
Osteopontin (SPP1) (Human)

Documents

References

1) Kim, J. H., et al., JAMA 287, 1671-1679 (2002) 2) Ashkar, S., et al., Science 287, 860-864 (2000) 3) Kojima, T and Kitamura, T., Nat. Biotechnol. 17, 487-490 (1999) 4) Reinholt, F. P., et al., PNAS 87, 4473-4475 (1990)