MBL

Anti-5-hydroxymethylcytosine (5hmC) pAb

Product Code:
 
MBL-PM077
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rabbit
Antibody Isotype:
 
Affinity Purified Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Shipping:
 
4°C
Storage:
 
-20°C
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CodeSizePrice
MBL-PM077100 ul£346.00
Quantity:
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This product comes from: United States.
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Further Information

Applications:
WB - Dot blot: 1:5,000 IP - hMeDIP: 2 ul/sample
Background:
DNA methylation is one of many critical epigenetic modifications. In most cases, cytosine (C) in DNA sequence is converted to 5-methylcytosine (5mC) with addition of a methyl group by the enzymatic activity of DNA methyltransferase. DNA methylation plays a role in the regulation of gene expression. It has been reported that abnormal DNA methylation level is involved in many diseases. 5-hydroxymethylcytosine (5hmC), a newly identified epigenetic modification following 5mC, is generated from oxidation of 5mC by the enzymatic activity of TET family proteins. 5hmC may function as a regulator of gene expression as well as 5mC.
Formulation:
PBS/50% glycerol, pH 7.2
Immunogen Translated:
BSA-conjugated 5-hydroxymethylcytidine
Target:
5-hydroxymethylcytosine (5hmC)

Documents