Leinco Technologies

Anti-Mouse IL-2 (Clone JES6-1A12) - DyLight® 550

Product Code:
 
LEI-I-1088
Product Group:
 
Primary Antibodies
Host Type:
 
Rat
Antibody Isotype:
 
IgG2a κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
JES6-1A12
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Flow Cytometry
  • Immunocytochemistry (ICC)
Shipping:
 
2-8°C
Storage:
 
This DyLight® 550 conjugate is stable when stored at 2-8°C. Do not freeze.
 

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CodeSizePrice
LEI-I-1088-50ug50 ug£159.00
Quantity:
LEI-I-1088-100ug100 ug£211.00
Quantity:
LEI-I-1088-200ug200 ug£291.00
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This product comes from: US.
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Further Information

Concentration:
0.2 mg/ml
Conjugate/Tag/Label:
DyLight® 550
Format:
This DyLight® 550 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Formulation:
This DyLight® 550 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Immunogen:
Purified Recombinant Mouse IL-2 (>98%)
Long Description:
IL-2 is a 17.2 kD cytokine signaling protein that is the regulator of the proliferative and suppressive phases of the immune response, and stimulates growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes. It functions as a primary regulator of T cell homeostasis. Il-2 regulates the activities of white blood cells and plays a role in the immune system via ?self? and ?non-self? discrimination. IL-2 is a prime candidate in immunotherapeutics for both increasing T cell levels/function and for augmenting vaccine-elicited viral-specific T cell responses. IL-2 signal can be transduced via 3 different signaling pathways that include the JAK-STAT, PI3K/Akt/mTOR and MAPK/ERK pathways. Aldesleukin is a form of recombinant interleukin-2 for the treatment of cancers including malignant melanoma and renal cell cancer. Furthermore, there is additional therapeutic potential for IL-2 mAb use with transplants and autoimmune disease.
NCBI Gene:
16183
Target:
IL-2

References

1. Schachter, J. et al. (2009) Cytotherapy 11: 206 2. Sodora, DL. et al. (2009) Curr HIV Res. 7: 83 3. Alcocer-Varela, J. et al. (2009) Autoimmun Rev. 9(1):34-9.