Leinco Technologies

Anti-Human CLC (Clone 138815)

Product Code:
 
LEI-C1462
Product Group:
 
Primary Antibodies
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2b
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
138815
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ambient
Storage:
 
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
 

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CodeSizePrice
LEI-C1462-25ug25 ug£375.00
Quantity:
LEI-C1462-500ug500 ug£785.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Conjugate/Tag/Label:
Purified No Carrier Protein
Format:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.4 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Formulation:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.4 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Immunogen:
E. coli-Derived Recombinant Human CLC (Accession # Q9UBD9)
Long Description:
Cardiotrophin-like cytokine (CLC) also known as novel neurotrophin-1/B cell stimulating factor-3 (NNT-1/BSF-3) is a member of the interleukin (IL)-6 family of cytokines.1 CLC is expressed highly in spleen and peripheral leukocytes2 and is a target-derived factor required for the survival of specific pools of motoneurons.3 CLC shows neuroprotective effects on retinal ganglion cells (RGCs) in vivo and might be a treatment option for chronic neurodegenerative eye diseases such as glaucoma.4
NCBI Gene:
23529
Target:
CLC

References

1. Taga, T. et al. (2002) Cytokine 18: 1 2. Shi, Y. et al. (1999) Biochemical Biophysical Res Communications 262: 132 3. Oppenheim, RW. et al. (2003) J Neurosci. 23: 8854 4. Wen, R. et al. (2005) Graefe's Archive for Clinical and Experimental Ophthalmol. 243: 1036