Leinco Technologies

Anti-Human CD30 Ligand (TNFSF8)

Product Code:
 
LEI-C1456
Product Group:
 
Primary Antibodies
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2a
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
116615
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
Ambient
Storage:
 
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
 

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CodeSizePrice
LEI-C1456-25ug25 ug£375.00
Quantity:
LEI-C1456-500ug500 ug£785.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Conjugate/Tag/Label:
Purified No Carrier Protein
Format:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Formulation:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Immunogen:
NS0-Derived Recombinant Human CD30 Ligand Extracellular Domain (Accession # P32971)
Long Description:
The CD30 ligand is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily. CD30L is expressed on the cell surface of activated T cells, B cells, and monocytes. Recombinant CD30L has been shown to co-stimulate T cells and to act as a mitogen for Hodgkin's disease derived cell lines. The receptor for CD30L, CD30/ TNFRSF8/CD153, is a type I cytokine receptor that is highly expressed by activated T cells, Hodgkin and Reed- Sternberg (H-RS) cells, and anaplastic large cell lymphoma cells. CD30 ligation by CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation and cell death by apoptosis.
NCBI Gene:
944
Target:
CD30 Ligand

References

1. Croager, EJ. et al. (1997) Biochim. Biophys. Acta. 1353:2312. Gruss, HJ. et al. (1994) Blood 83:15213. Wendtner, CM. et al. (1995) Cancer Res. 55:41574. Fischer, M. et al. (2006) J. Clin. Invest. 116:27485. Blazar, BR. et al. (2004) J. Immunol. 173:2933