Leinco Technologies

Anti-Mouse CD25 - FITC

Product Code:
 
LEI-C1191
Product Group:
 
Primary Antibodies
Host Type:
 
Rat
Antibody Isotype:
 
IgG1 λ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
PC61
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
Ambient
Storage:
 
This Fluorescein conjugate is stable when stored at 2-8°C. Do not freeze.
 

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CodeSizePrice
LEI-C1191-100ug100 ug£156.00
Quantity:
LEI-C1191-500ug500 ug£276.00
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Further Information

Antigen Distribution:
CD25 is expressed in activated T cells and B cells, thymocyte subset, pre-B cells, T regulatory cells.
Concentration:
0.2 mg/ml
Conjugate/Tag/Label:
Fluorescein (FITC)
Format:
This Fluorescein (FITC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Formulation:
This Fluorescein (FITC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Immunogen:
IL-2-dependent cytolytic mouse T-cell clone B6.1
Long Description:
CD25, a 55 kD type I transmembrane glycoprotein, has been shown to play roles in lymphocyte differentiation, activation, and proliferation. Many resting memory T cells constitutively express IL2RA. It functions as the receptor for HTLV-1, resulting in its expression on neoplastic cells in adult T cell lymphoma/leukemia. CD25 (sIL-2R) has been used to track disease progression. Some additional clinical applications include Chagas disease, a disease characterized by a decline of CD25 expression on immune cells, and Multiple sclerosis, in which treatments with mAbs target CD25.
NCBI Gene:
16184
Target:
CD25

References

1. Warren J. Leonard et al. (2002) The EMBO Journal 21: 3051 2. FW Alt et al. (1995) Immunity 3: 521 3. Greene WC et al. (1990) J Invest Dermatol. 94: 27S