Leinco Technologies

Anti-Human IL-21R (NT)

Product Code:
 
LEI-I-356
Product Group:
 
Primary Antibodies
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
Ambient
Storage:
 
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
 

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CodeSizePrice
LEI-I-356-20ug20 ug£199.00
Quantity:
LEI-I-356-0.1mg0.1 mg£591.00
Quantity:
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This product comes from: US.
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Further Information

Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Purified No Carrier Protein
Format:
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Formulation:
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Immunogen:
PN:I-357
Long Description:
Interleukin 21 receptor (IL-21R) is a novel member of the class-I-cytokine-receptor family and is selectively expressed in lymphoid tissues. IL21R shows strong sequence homologies to the interleukin-4 receptor alpha chain gene (IL4RA).1 IL-21R is an important amplifier of alternative macrophage activation. Collectively, these results illustrate an essential function for the IL-21R in the development of pathogen-induced Th2 responses, which may have relevance in therapies for both inflammatory and chronic fibrotic diseases.2 IL-21/IL-21R system may represent a new target for the treatment of Adult T-cell leukaemia (ATL).3
NCBI Gene:
50615
Target:
Interleukin-21 Receptor

References

1. Hackstein H et al. (2003) Genes Immun. 4: 228 2. Wynn TA et al. (2006) J Clin Invest. 116: 2044 3. Uchiyama T et al. (2005) Br J Haematol. 128: 169