ProSci

LpxT Peptide

Product Code:
 
PSI-10051P
Product Group:
 
Peptides
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Application:
 
Blocking
Shipping:
 
Blue Ice
Storage:
 
Store LpxT peptide at -20°C, stable for one year.
 

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CodeSizePrice
PSI-10051P-0.05mg0.05mg£166.00
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Further Information

Additional Names:
Lipid A 1-diphosphate synthase, Kdo(2)-lipid A phosphotransferase, Undecaprenyl pyrophosphate:lipid A 1-phosphate phosphotransferase, Eck2168, yeiU
Application Note:
The peptide is used for blocking the activity of the LpxT antibody.
Background:
LpxT is involved in the modification of the lipid A domain of lipopolysaccharides (LPS) and transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1-diphosphate as well as contributes to the recycling of undecaprenyl phosphate (C55-P). In vitro, it has low undecaprenyl-diphosphate phosphatase activity.
Background References:
  • LpxT is involved in the modification of the lipid A domain of lipopolysaccharides (LPS) and transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1-diphosphate as well as contributes to the recycling of undecaprenyl phosphate (C55-P). In vitro, it has low undecaprenyl-diphosphate phosphatase activity.
  • Touze, et al. Mol Microbiol. 2008; 67(2): 267-77.
  • Tatar, et al. Microbiology 2007; 153(Pt8): 2518-2529.
Buffer:
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Concentration:
200 ug/mL
NCBI Gene ID #:
946693
NCBI Official Name:
lipid A-core phosphotransferase
NCBI Official Symbol:
lpxT
NCBI Organism:
Escherichia coli str. K-12 substr. MG1655
Peptide aa Location:
14 amino acids carboxy terminus of E. coli LpxT.
Physical State:
Liquid
Protein Accession #:
P76445.2
Protein GI Number:
3183418
Swissprot #:
P76445
User Note:
Optimal dilutions for each application to be determined by the researcher.

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