MBL

MESACUP-2 TEST Desmoglein 1

Product Code:
 
MBLJ-7881E
Product Group:
 
ELISA Kits
Supplier:
 
MBL
Regulatory Status:
 
IVD
Target Species:
 
Human
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
 

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MBLJ-7881E48 wells£234.00
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This product comes from: United States.
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Further Information

Description:
The MESACUP™-2 TEST Desmoglein 1 measures anti-Dsg1 antibodies present in the serum by ELISA. Desmoglein 1 (Dsg1) is a desmosomal cadherin expressed in stratified squamous epithelia and the target antigen in pemphigus foliaceus (PF). PF is an autoimmune blistering disease of skin and characterized clinically by small flaccid blisters and scaly, crusted erosions, and histologically by intraepidermal blister formation due to loss of cell adhesion of keratinocytes. Anti-Dsg1 IgG autoantibodies are detected in sera from patients with PF and play a pathogenic role in blister formation in PF.