AdipoGen Life Sciences

ANGPTL3 (human) ELISA Kit

Product Code:
 
AG-45A-0014Y
Product Group:
 
ELISA Kits
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
BLUE ICE
Storage:
 
Short term: +4°C. Long term: +4°C
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AG-45A-0014YEK-KI0196 wells£570.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
Angiopoietin-like Protein 3; Angiopoietin-5; ANG-5
Assay Type:
Sandwich
Detection Type:
Colorimetric
EClass:
32160000
Handling Advice:
After standard reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Plate and reagents should reach room temperature before use.
Long Description:
ELISA Assay. Detects human ANGPTL3. Does not cross-react with mouse ANGPTL3, human ANGPTL4, human ANGPTL6, human ANGPTL7 or human ANGPTL2. Colorimetric assay. Sample Types: Cell Culture Supernatant, Plasma, Serum. Range: 0.156 to 10ng/ml. Sensitivity: 75pg/ml. Seven proteins containing an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain, both characteristics of angiopoietins, have been identified and therefore designated angiopoietin-like proteins 1-7 (ANGPTL 1-7). ANGPTL3 and ANGPTL6 (Angiopoietin-related growth factor; AGF), among others, function to regulate angiogenesis and also appear to directly regulate lipid, glucose, and energy metabolism. ANGPTL3 plasma levels are increased in a mouse model of diabetes mellitus.
NCBI, Uniprot Number:
A0JLS0
Package Type:
Box
Product Description:
Seven proteins containing an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain, both characteristics of angiopoietins, have been identified and therefore designated angiopoietin-like proteins 1-7 (ANGPTL 1-7). ANGPTL3 and ANGPTL6 (Angiopoietin-related growth factor; AGF), among others, function to regulate angiogenesis and also appear to directly regulate lipid, glucose, and energy metabolism. ANGPTL3 plasma levels are increased in a mouse model of diabetes mellitus.
Range:
0.156 to 10ng/ml
Sample Type:
Cell Culture Supernatant, Plasma, Serum
Sensitivity:
75pg/ml
Specificity:
Detects human ANGPTL3. Does not cross-react with mouse ANGPTL3, human ANGPTL4, human ANGPTL6, human ANGPTL7 or human ANGPTL2.
Transportation:
Non-hazardous
UNSPSC Category:
ELISA Kits
UNSPSC Number:
41116126
Use & Stability:
12 months after the day of manufacturing. See expiry date on ELISA Kit box.

References

Exercise training restores the endothelial response to vascular growth factors in patients with stable coronary artery disease: E.B. Beck, et al.; Eur. J. Prev. Cardiol. 19, 412 (2012) | Characterization of three kindreds with familial combined hypolipidemia caused by loss-of-function mutations of ANGPTL3: L. Pisciotta, et al.; Circ. Cardiovasc. Gent. 5, 42 (2012) | Atypical angiopoietin-like protein that regulates ANGPTL3: F. Quagliarini, et al.; PNAS 109, 19751 (2012) | Clinical characteristics and plasma lipids in subjects with familial combined hypolipidemia: a pooled analysis: I. Minicocci, et al.; J. Lipid Res. 54, 3481 (2013) | Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation: G. Flehmig, et al.; PLos One 9, e99785 (2014) | Persistence of HCV in Acutely-Infected Patients Depletes C24-Ceramide and Upregulates Sphingosine and Sphinganine Serum Levels: G. Grammatikos, et al.; Int. J. Mol. Sci. 17, 922 (2016) | ANGPTL3 and ANGPTL8 in Thai subjects with hyperalphalipoproteinemia and severe hypertriglyceridemia: C. Kaewkrasaesin, et al.; J. Clin. Lipidol. in press (2021)