TargetMol

Rotenone

Product Code:
 
TAR-T2970
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2970-500mg500mg£104.00
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Quantity:
TAR-T2970-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T2970-1g1g£111.00
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This product comes from: United States.
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Further Information

Bioactivity:
Rotenone is a botanical insecticide that is an inhibitor of mitochondrial electron transport. Rotenone is widely distributed in the Leguminosae (Papilionoideae).
CAS:
83-79-4
Formula:
C23H22O6
Molecular Weight:
394.423
Pathway:
Metabolism; Apoptosis; Autophagy
Purity:
0.9948
SMILES:
COc1cc2OC[C@H]3Oc4c5C[C@@H](Oc5ccc4C(=O)[C@H]3c2cc1OC)C(C)=C
Target:
Apoptosis; Dehydrogenase; Mitochondrial Metabolism; p53; Autophagy

References

1. Khadrawy YA, et al. Cerebellar neurochemical and histopathological changes in rat model of Parkinson's disease induced by intrastriatal injection of rotenone. Gen Physiol Biophys. 2016 Nov 30. 2. Guan Q, et al. RNA-Seq Expression Analysis of Enteric Neuron Cells with Rotenone Treatment and Prediction of Regulated Pathways. Neurochem Res. 2016 Nov 30. 3. Kishore Kumar SN, et al. Morinda citrifolia mitigates rotenone-induced striatal neuronal loss in male Sprague-Dawley rats by preventing mitochondrial pathway of intrinsic apoptosis. Redox Rep. 2016 Nov 24:1-12. 4. Zhang ZN, et al. Subcutaneous rotenone rat model of Parkinson's disease: dose exploration study. Brain Res. 2016 Nov 19. pii: S202006-81993(16)30776-4. 5. Li Y, Sun H, Tian Z, et al. The determination of Plutella xylostella (L.) GSTs (PxGSTs) involved in the detoxification metabolism of Tolfenpyrad[J]. Pest Management Science. 2020.