TargetMol

Pyrrole-2-carboxylic acid

Product Code:
 
TAR-T4716
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4716-500mg500mg£103.00
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TAR-T4716-1mL1 mL * 10 mM (in DMSO)£107.00
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Quantity:
TAR-T4716-1g1g£109.00
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Further Information

Bioactivity:
Pyrrole-2-carboxylic acid was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase. The latter relationship results from the lability of the direct oxidation product, A'-pyrroline-4-hydroxy-2-carboxylic acid, which loses water spontaneously to form the pyrrole. A similar reaction is catalyzed by the more specific allohydroxy-D-proline oxidase of Pseudomonas. In whole animal observations, pyrrole-2-carboxylate (PCA) ' was identified in rat or human urine after administration of the D-isomers of hydroxyproline, a finding ascribable to the action of D-amino acid oxidase. Urinary excretion of N-(pyrrole-2-carboxyl) glycine has been reported in a 5-year-old affected with type II hyperprolinemia; The child has mild developmental delay, recurrent seizures of the grand mal type and EEG alterations.
CAS:
634-97-9
Formula:
C5H5NO2
Molecular Weight:
111.1
Pathway:
Metabolism
Purity:
0.9995
SMILES:
OC(=O)c1ccc[nH]1
Target:
Endogenous Metabolite

References

He XX, et al. Pelopuradazole, a new imidazole derivative alkaloid from the marine bacteria Pelomonas puraquae sp. nov. Nat Prod Res. 2014;28(9):680-2.