TargetMol

CAY10487

Product Code:
 
TAR-T35985
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35985-5mg5mg£850.00
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Quantity:
TAR-T35985-50mg50mg£1,661.00
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Quantity:
TAR-T35985-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall. CAY10487 inhibits formation of fatty streak lesions of the thoracic aorta in high cholesterol-fed rabbits without affecting plasma lipid profiles or significantly inhibiting ACAT-1 or ACAT-2 activity. The percent area occupied by the atherosclerotic lesion in rabbits supplemented with 0.05% CAY10487 in the diet was 16.1% compared to 53.5% in control rabbits. CAY10487 also exhibits antioxidant activity, inhibiting copper-mediated oxidation of low-density lipoprotein by about 75% at a concentration of 2 μM.
CAS:
778624-05-8
Formula:
C13H15NO5
Molecular Weight:
265.3
Purity:
0.98
SMILES:
COC(=O)[C@H](C)NC(=O)C=C/c1ccc(O)c(O)c1