TargetMol

(+)-δ-Cadinene

Product Code:
 
TAR-T35409
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35409-50mg50mg£112.00
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TAR-T35409-100mg100mg£149.00
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TAR-T35409-500mg500mg£273.00
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Further Information

Bioactivity:
(+)-δ-Cadinene is a sesquiterpene that has been found in upland cotton (G. hirsutum) and has antibacterial, insecticidal, and anticancer activities.1,2,3,4It is active againstS. pneumoniae(MIC = 31.25 μg/ml) and induces mortality inA. stephensi,A. aegypti, andC. quinquefasciatusthird instar larvae (LC50s = 8.23, 9.03, and 9.86 μg/ml, respectively).2,3(+)-δ-Cadinene (10, 50, and 100 μM) induces apoptosis in and inhibits proliferation of OVCAR-3 human ovarian cancer cells.4
CAS:
483-76-1
Formula:
C15H24
Molecular Weight:
204.4
Pathway:
Apoptosis|Microbiology/Virology
Purity:
0.98
SMILES:
CC([C@H]1[C@@]2([H])C(CCC(C)=C2)=C(CC1)C)C
Target:
Apoptosis|Antibacterial

References

Chen XY, et al. Cloning and heterologous expression of a second (+)-delta-cadinene synthase from Gossypium arboreum. J Nat Prod. 1996;59(10):944-951. Meng YL, et al. Coordinated accumulation of (+)-delta-cadinene synthase mRNAs and gossypol in developing seeds of Gossypium hirsutum and a new member of the cad1 family from G. arboreum. J Nat Prod. 1999;62(2):248-252. Yoshikuni Y, et al. Engineering cotton (+)-delta-cadinene synthase to an altered function: germacrene D-4-ol synthase. Chem Biol. 2006;13(1):91-98. Tan XP, et al. Expression pattern of (+)-delta-cadinene synthase genes and biosynthesis of sesquiterpene aldehydes in plants of Gossypium arboreum L. Planta. 2000;210(4):644-651.