TargetMol

Megestrol acetate

Product Code:
 
TAR-T1284
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1284-500mg500mg£107.00
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Quantity:
TAR-T1284-1mL1 mL * 10 mM (in DMSO)£111.00
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Quantity:
TAR-T1284-1g1g£116.00
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This product comes from: United States.
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Further Information

Bioactivity:
Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia.
CAS:
595-33-5
Formula:
C24H32O4
Molecular Weight:
384.516
Pathway:
Microbiology/Virology; Autophagy; Endocrinology/Hormones; Proteases/Proteasome;
Purity:
0.9972
SMILES:
[H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C=C(C)C2=CC(=O)CC[C@]12C
Target:
Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; HIV Protease; Autophagy

References

1. Kelicen Ugur P, et al. Eur J Pharmacol, 2011, 654(3), 217-225. 2. Sung JH, et al. Stem Cells Transl Med. 2015 Jul;4(7):789-99. 3. Han J, et al. Aquat Toxicol,2014, 150, 66-72. 4. Peterson ME, et al. Res Vet Sci,1987, 42(3), 354-357. 5. McCarthy HD, et al. Eur J Pharmacol,1994, 265(1-2), 99-102.