TargetMol

Naphthoquine phosphate

Product Code:
 
TAR-T12174
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
Naphthoquine phosphate is antimalarial drug.
CAS:
173531-58-3
Formula:
C24H34ClN3O9P2
Molecular Weight:
605.95
Purity:
0.98
SMILES:
OP(O)(O)=O.OP(O)(O)=O.CC(C)(C)NCc1cc(Nc2ccnc3cc(Cl)ccc23)c2CCCCc2c1O

References

1. Qu HY, et al. Single-dose safety, pharmacokinetics, and food effects studies of compound naphthoquine phosphate tablets in healthy volunteers. J Clin Pharmacol. 2010 Nov;50(11):1310-8. 2. Tun T, et al. Efficacy of oral single dose therapy with artemisinin-naphthoquine phosphate in uncomplicated falciparum malaria. Acta Trop. 2009 Sep;111(3):275-8. 3. Wang JY, et al. [Therapeutic efficacy of naphthoquine phosphate combined with artemisinine against Plasmodium knowlesi]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2008 Dec 30;26(6):442-444. 4. Wang JY, et al. Naphthoquine phosphate and its combination with artemisinine. Acta Trop. 2004 Feb;89(3):375-81. 5. Wang SQ, et al. Therapeutic effect of dihydroartemisinin combined with naphthoquine phosphate in patients with falciparum malaria .Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2002;20(3):180-2. 6. El-Beshbishi SN, et al. First insight into the effect of single oral dose therapy with artemisinin-naphthoquine phosphate combination in a mouse model of Schistosoma mansoni infection. Int J Parasitol. 2013 Jun;43(7):521-530.