TargetMol

Cefepime

Product Code:
 
TAR-T0868L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T0868L-100mg100mgEnquire
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TAR-T0868L-50mg50mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Cefepime is an antibiotic. Cefepime has been shown to be effective against febrile neutropenia.
CAS:
88040-23-7
Formula:
C19H24N6O5S2
Molecular Weight:
480.56
Purity:
0.98
SMILES:
C[N+]1(CC(CS[C@]2([H])[C@@H]3NC(/C(C4=CSC(N)=N4)=NOC)=O)=C(C([O-])=O)N2C3=O)CCCC1

References

1. Tamma PD, Girdwood SC, Gopaul R, Tekle T, Roberts AA, Harris AD, Cosgrove SE, Carroll KC. The use of cefepime for treating AmpC ?-lactamase-producing Enterobacteriaceae. Clin Infect Dis. 2013 Sep;57(6):781-8. doi: 10.1093/cid/cit395. Epub 2013 Jun 11. PubMed PMID: 23759352. 2. Saito H, Takahashi K, Okuno M, Saka H, Imaizumi K, Hasegawa Y, Tanikawa Y, Yamamoto M, Taniguchi H, Shindoh J, Suzuki R, Shimokata K; Central Japan Lung Study Group. Cefepime monotherapy for febrile neutropenia in patients with lung cancer. J Infect Chemother. 2014 Jun;20(6):365-9. doi: 10.1016/j.jiac.2014.02.002. Epub 2014 Mar 26. PubMed PMID: 24679653. 3. Fugate JE, Kalimullah EA, Hocker SE, Clark SL, Wijdicks EF, Rabinstein AA. Cefepime neurotoxicity in the intensive care unit: a cause of severe, underappreciated encephalopathy. Crit Care. 2013 Nov 7;17(6):R264. doi: 10.1186/cc13094. PubMed PMID: 24200036; PubMed Central PMCID: PMC4057506. 4. Nguyen HM, Shier KL, Graber CJ. Determining a clinical framework for use of cefepime and ?-lactam/?-lactamase inhibitors in the treatment of infections caused by extended-spectrum-?-lactamase-producing Enterobacteriaceae. J Antimicrob Chemother. 2014 Apr;69(4):871-80. doi: 10.1093/jac/dkt450. Epub 2013 Nov 20. Review. PubMed PMID: 24265230.