TargetMol

Hydroxyurea

Product Code:
 
TAR-T0676
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0676-500mg500mg£107.00
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Quantity:
TAR-T0676-1mL1 mL * 10 mM (in DMSO)£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T0676-1g1g£113.00
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This product comes from: United States.
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Further Information

Bioactivity:
Hydroxyurea, an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
CAS:
127-07-1
Formula:
CH4N2O2
Molecular Weight:
76.055
Pathway:
Cell Cycle/Checkpoint; Apoptosis; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome; Autophagy
Purity:
0.9992
SMILES:
NC(=O)NO
Target:
Apoptosis; HIV Protease; DNA/RNA Synthesis; Autophagy

References

1. Lori F, et al. Clin Infect Dis. 2000, 30 Suppl 2:S193-7. 2. Zala C, et al. Clin Infect Dis. 2000, Suppl 2:S143-50. 3. Watanapokasin Y, et al. Exp Hematol. 2005, 33(12):1486-92. 4. Boucher PD, et al. Gene Ther. 2002, 9(15):1023-30. 5. Lebensburger JD, et al. Hydroxyurea therapy requires HbF induction for clinical benefit in a sickle cell mouse model. Haematologica. 2010 Sep;95(9):1599-603.