TargetMol

ZINC-3573

Product Code:
 
TAR-T29221
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29221-2mg2mg£102.00
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TAR-T29221-5mg5mg£122.00
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TAR-T29221-1mL1 mL * 10 mM (in DMSO)£127.00
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TAR-T29221-10mg10mg£148.00
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TAR-T29221-25mg25mg£254.00
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TAR-T29221-50mg50mg£346.00
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Quantity:
TAR-T29221-100mg100mg£470.00
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This product comes from: United States.
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Further Information

Bioactivity:
ZINC-3573 is a potent and highly selective MRGPRX2 probe. ZINC-3573 activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.
CAS:
2089389-15-9
Formula:
C18H21N5
Molecular Weight:
307.401
Purity:
0.98
SMILES:
CN(C)[C@@H]1CCN(C1)c1cc(nc2ccnn12)-c1ccccc1

References

1. Lansu K, Karpiak J, Liu J, Huang XP, McCorvy JD, Kroeze WK, Che T, Nagase H, Carroll FI, Jin J, Shoichet BK, Roth BL. In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat Chem Biol. 2017 May;13(5):529-536. doi: 10.1038/nchembio.2334. Epub 2017 Mar 13. PubMed PMID: 28288109; PubMed Central PMCID: PMC5391270.