TargetMol

HS38

Product Code:
 
TAR-T27554
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T27554-5mg5mg£108.00
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TAR-T27554-1mL1 mL * 10 mM (in DMSO)£112.00
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TAR-T27554-10mg10mg£124.00
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TAR-T27554-25mg25mg£181.00
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TAR-T27554-50mg50mg£249.00
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TAR-T27554-100mg100mg£360.00
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TAR-T27554-200mg200mg£503.00
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This product comes from: United States.
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Further Information

Bioactivity:
HS38 is a potent and selective inhibitor for DAPK1 and ZIPK.
CAS:
1030203-81-6
Formula:
C14H12ClN5O2S
Molecular Weight:
349.79
Pathway:
Apoptosis
Purity:
0.98
SMILES:
CC(Sc1nc2n(ncc2c(=O)[nH]1)-c1cccc(Cl)c1)C(N)=O
Target:
DAPK

References

1. MacDonald JA, Sutherland C, Carlson DA, Bhaidani S, Al-Ghabkari A, Sw?rd K, Haystead TA, Walsh MP. A Small Molecule Pyrazolo[3,4-d]Pyrimidinone Inhibitor of Zipper-Interacting Protein Kinase Suppresses Calcium Sensitization of Vascular Smooth Muscle. Mol Pharmacol. 2016 Jan;89(1):105-17. doi: 10.1124/mol.115.100529. Epub 2015 Oct 13. PubMed PMID: 26464323. 2. Carlson DA, Franke AS, Weitzel DH, Speer BL, Hughes PF, Hagerty L, Fortner CN, Veal JM, Barta TE, Zieba BJ, Somlyo AV, Sutherland C, Deng JT, Walsh MP, MacDonald JA, Haystead TA. Fluorescence linked enzyme chemoproteomic strategy for discovery of a potent and selective DAPK1 and ZIPK inhibitor. ACS Chem Biol. 2013 Dec 20;8(12):2715-23. doi: 10.1021/cb400407c. Epub 2013 Oct 17. PubMed PMID: 24070067; PubMed Central PMCID: PMC4445880. 3. Lorenz E, Lastovica A, Owen RJ. Subtyping of Campylobacter jejuni Penner serotypes 9, 38 and 63 from human infections, animals and water by pulsed field gel electrophoresis and flagellin gene analysis. Lett Appl Microbiol. 1998 Mar;26(3):179-82. PubMed PMID: 9569705.