TargetMol

AN0128

Product Code:
 
TAR-T26624
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T26624-100mg100mgEnquire
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TAR-T26624-50mg50mgEnquire
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Further Information

Bioactivity:
AN 0128 is a tumour necrosis factor alpha (TNF-α) inhibitor.
CAS:
872044-70-7
Formula:
C20H16BCl2NO3
Molecular Weight:
400.06
Purity:
0.98
SMILES:
Cc1ccc(cc1Cl)B(OC(=O)c1ncccc1O)c1ccc(C)c(Cl)c1

References

1. Baker SJ, Akama T, Zhang YK, Sauro V, Pandit C, Singh R, Kully M, Khan J, Plattner JJ, Benkovic SJ, Lee V, Maples KR. Identification of a novel boron-containing antibacterial agent (AN0128) with anti-inflammatory activity, for the potential treatment of cutaneous diseases. Bioorg Med Chem Lett. 2006 Dec 1;16(23):5963-7. PubMed PMID: 16997550. 2. Luan Q, Desta T, Chehab L, Sanders VJ, Plattner J, Graves DT. Inhibition of experimental periodontitis by a topical boron-based antimicrobial. J Dent Res. 2008 Feb;87(2):148-52. PubMed PMID: 18218841. 3. Ciaravino V, Plattner J, Chanda S. An assessment of the genetic toxicology of novel boron-containing therapeutic agents. Environ Mol Mutagen. 2013 Jun;54(5):338-46. doi: 10.1002/em.21779. PubMed PMID: 23625818.