TargetMol

SR144528

Product Code:
 
TAR-T16928
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16928-1mg1mg£99.00
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TAR-T16928-5mg5mg£140.00
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TAR-T16928-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T16928-10mg10mg£197.00
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TAR-T16928-25mg25mg£357.00
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TAR-T16928-50mg50mg£499.00
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Quantity:
TAR-T16928-100mg100mg£688.00
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Further Information

Bioactivity:
SR144528 is an effective and selective antagonist of the CB2 receptor (Ki: 0.6 nM).
CAS:
192703-06-3
Formula:
C29H34ClN3O
Molecular Weight:
476.06
Pathway:
GPCR/G Protein
Purity:
0.98
SMILES:
[H][C@@]12CC[C@@](C)(C1)[C@H](NC(=O)c1cc(-c3ccc(Cl)c(C)c3)n(Cc3ccc(C)cc3)n1)C2(C)C
Target:
Cannabinoid Receptor

References

1. Rinaldi-Carmona M, et al. SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor. J Pharmacol Exp Ther. 1998 Feb;284(2):644-50. 2. Thewke D, et al. AM-251 and SR144528 are acyl CoA:cholesterol acyltransferase inhibitors. Biochem Biophys Res Commun. 2009 Apr 3;381(2):181-6. 3. Abalo R, et al. The cannabinoid antagonist SR144528 enhances the acute effect of WIN 55,212-2 on gastrointestinal motility in the rat. Neurogastroenterol Motil. 2010 Jun;22(6):694-e206.