TargetMol

Oxyphenbutazone

Product Code:
 
TAR-T16419
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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This product comes from: United States.
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Further Information

Bioactivity:
Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is a phenylbutazone derivative. It has an anti-inflammatory effect. Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis.
CAS:
129-20-4
Formula:
C19H20N2O3
Molecular Weight:
324.38
Pathway:
Immunology/Inflammation; Neuroscience
Purity:
0.98
SMILES:
CCCCC1C(=O)N(N(C1=O)c1ccc(O)cc1)c1ccccc1
Target:
COX

References

1. Saleem S, et al. Oxyphenbutazone promotes cytotoxicity in rats and Hep3B cellsvia suppression of PGE2 and deactivation of Wnt/?-catenin signaling pathway. Mol Cell Biochem. 2018 Jul;444(1-2):187-196. 2. Gold B, et al. Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16004-11.